Orphenadrine hydrochloride 11442 Smiles: CC(C)C[C@H](NC(=O)[C@H](CC1C=CC(=CC=1)OP(O)(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(O)=O

Smiles: CC(C)C[C@H](NC(=O)[C@H](CC1C=CC(=CC=1)OP(O)(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(O)=O

InChiKey: IFUKBHBISRAZTF-UHFFFAOYSA-M

Chemical Name: 4-cyclohexanecarbonyl-4

and preS but not X promoter activities

20)11-5-10(6-12(7-11)17(21

Orphenadrine hydrochloride 11442 Smiles: CC(C)C[C@H](NC(=O)[C@H](CC1C=CC(=CC=1)OP(O)(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(O)=OOrphenadrine hydrochloride is an uncompetitive N methyl D aspartate (NMDA) receptor antagonist with Ki of 6. 0 0. 7 M. IC50 value: 6. 0 0. 7 M (Ki) Target: NMDA Receptor Orphenadrine has been used as an antiparkinsonian, antispastic and analgesic drug. Orphenadrine inhibits [3H]MK 801 binding to the phencyclidine (PCP) binding site of the N methyl D aspartate (NMDA) receptor in homogenates of postmortem human frontal cortex with a Ki value of 6. 0 0.